Lysine‐241 Has a Role in Coupling 2OG Turnover with Substrate Oxidation During KDM4‐Catalysed Histone Demethylation
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DOI: 10.1002/cbic.201800002
Abstract: The JmjC histone lysyl demethylases (KDMs) play important roles in modulating histone methylation states and have the potential to be regulated by oxygen availability. Lys241 of the KDM4 subfamily is proposed to be important in… read more here.
Keywords: substrate oxidation; oxidation; role coupling; lysine 241 ... See more keywords