Post‐Assembly Modification of Protein Cages by Ubc9‐Mediated Lysine Acylation
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DOI: 10.1002/cbic.202200332
Abstract: Although viruses have been successfully repurposed as vaccines, antibiotics, and anticancer therapeutics, they also raise concerns regarding genome integration and immunogenicity. Virus‐like particles and non‐viral protein cages represent a potentially safer alternative but often lack… read more here.
Keywords: modification; lysine acylation; protein cages; protein ... See more keywords
Lysine acylation causes collateral damage in inborn errors of metabolism
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DOI: 10.1126/scitranslmed.abq4863
Abstract: Posttranslational modifications contribute to the pathology of methylmalonic acidemia and may be targetable via an acylation-resistant sirtuin (Head et al., this issue). Description Posttranslational modifications contribute to the pathology of methylmalonic acidemia and may be… read more here.
Keywords: lysine acylation; acylation causes; pathology; collateral damage ... See more keywords
Lysine Acylation Modification Landscape of Brucella abortus Proteome and its Virulent Proteins
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DOI: 10.3389/fcell.2022.839822
Abstract: The myriad of posttranslational modifications (PTMs) of proteins that occur in all living cells are crucial to all kinds of biological processes. Brucella is an intracellular parasitic bacterium that can cause chronic diseases in both… read more here.
Keywords: abortus; ptms; biological processes; lysine acylation ... See more keywords