Effects of lysine 2-hydroxyisobutyrylation on bacterial FabI activity and resistance to triclosan.
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DOI: 10.1016/j.biochi.2021.01.011
Abstract: Lysine 2-hydroxyisobutyrylation (Khib) is a novel protein posttranslational modification conserved in eukaryotes and prokaryotes. However, the biological significance of Khib remains largely unknown. Here, through screening the proteome-wide Khib modification sites in bacteria using a… read more here.
Keywords: fabi activity; khib; fabi; resistance ... See more keywords
Quantitative Proteomics Reveals the Role of Lysine 2-Hydroxyisobutyrylation Pathway Mediated by Tip60
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DOI: 10.1155/2022/4571319
Abstract: Lysine 2-hydroxyisobutyrylation (Khib) is a new type of posttranslational modifications (PTMs) extensively reported on eukaryotic cell histones. It is evolutionarily conserved and participates in diverse important biological processes, such as transcription and cell metabolism. Recently,… read more here.
Keywords: mediated tip60; khib; lysine hydroxyisobutyrylation; khib sites ... See more keywords
The Landscape and Potential Regulatory Mechanism of Lysine 2-Hydroxyisobutyrylation of Protein in End-Stage Renal Disease.
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DOI: 10.1159/000518424
Abstract: BACKGROUND Acetylation has a vital role in the pathogenesis of end-stage renal disease (ESRD). Lysine 2-hydroxyisobutyrylation (Khib) is a novel type of acetylation. In this study, we aimed to reveal the key features of Khib… read more here.
Keywords: renal disease; hydroxyisobutyrylation; stage renal; end stage ... See more keywords
Global analysis of lysine 2-hydroxyisobutyrylation during Fusarium graminearum infection in maize
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DOI: 10.3389/fpls.2022.1000039
Abstract: Proteins post-translational modification (PTMs) is necessary in the whole life process of organisms. Among them, lysine 2-hydroxyisobutyrylation (Khib) plays an important role in protein synthesis, transcriptional regulation, and cell metabolism. Khib is a newly identified… read more here.
Keywords: fusarium graminearum; infection; graminearum infection; lysine hydroxyisobutyrylation ... See more keywords