Improving lysine production through construction of an Escherichia coli enzyme‐constrained model
Sign Up to like & getrecommendations! Published in 2020 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.27485
Abstract: Microbial cell factories are widely used for the production of high‐value chemicals. However, maximizing production titers is made difficult by the complicated regulatory mechanisms of these cell platforms. Here, kcat values were incorporated to construct… read more here.
Keywords: coli enzyme; production; escherichia coli; enzyme constrained ... See more keywords
Enhancement of ε-poly-l-lysine production in Streptomyces griseofuscus by addition of exogenous astaxanthin
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DOI: 10.1007/s00449-020-02372-y
Abstract: Addition of exogenous astaxanthin for improving ε-poly-l-lysine (ε-PL) production in Streptomyces griseofuscus was investigated in this study. By this unique strategy, the ε-PL production in shaker-flask fermentation was 2.48 g/L, which was 67.5% higher than… read more here.
Keywords: poly lysine; exogenous astaxanthin; production; addition ... See more keywords
Enhancement of anaerobic lysine production in Corynebacterium glutamicum electrofermentations.
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DOI: 10.1016/j.bioelechem.2017.06.001
Abstract: It has been suggested that application of electric potential can affect lysine producing fermentations, although experimental evidence is lacking. To study this hypothesis we used the lysine producer Corynebacterium glutamicum ZW04, and we exposed it… read more here.
Keywords: corynebacterium glutamicum; glutamicum; lysine; lysine production ... See more keywords
Overexpression of thermostable meso-diaminopimelate dehydrogenase to redirect diaminopimelate pathway for increasing L-lysine production in Escherichia coli
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DOI: 10.1038/s41598-018-37974-w
Abstract: Dehydrogenase pathway, one of diaminopimelate pathway, is important to the biosynthesis of L-lysine and peptidoglycan via one single reaction catalyzed by meso-diaminopimelate dehydrogenase (DapDH). In this study, the thermostable DapDH was introduced into diaminopimelate pathway… read more here.
Keywords: dehydrogenase; pathway; diaminopimelate; diaminopimelate pathway ... See more keywords