Global profiling of lysine succinylation in human lungs
Sign Up to like & getrecommendations! Published in 2022 at "PROTEOMICS"
DOI: 10.1002/pmic.202100381
Abstract: The lysine succinylation (Ksucc) is involved in many core energy metabolism pathways and affects the metabolic process in mitochondria, making this modification highly valuable for studying diseases related to mitochondrial disorders. In this paper, we… read more here.
Keywords: human lungs; succinylation human; succinylation; global profiling ... See more keywords
Skeletal muscle of torpid Richardson's ground squirrels (Urocitellus richardsonii) exhibits a less active form of citrate synthase associated with lowered lysine succinylation.
Sign Up to like & getrecommendations! Published in 2021 at "Cryobiology"
DOI: 10.1016/j.cryobiol.2021.06.006
Abstract: Hibernation is a metabolic/physiological strategy employed by many mammals to cope with periods when energy usage is greater than its input. Animals undergoing hibernation need to greatly reduce their metabolic rate and reshape their catabolic… read more here.
Keywords: citrate synthase; skeletal muscle; muscle; lysine succinylation ... See more keywords
Sirtuin 5-Mediated Lysine Desuccinylation Protects Mitochondrial Metabolism Following Subarachnoid Hemorrhage in Mice
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DOI: 10.1161/strokeaha.121.034850
Abstract: Supplemental Digital Content is available in the text. Background and Purpose: Sirt5 (Sirtuin 5) desuccinylates multiple metabolic enzymes and plays an important role in maintaining energy homeostasis. The goal of this study was to determine… read more here.
Keywords: sah; sirt5; metabolism; synthase ... See more keywords
An Improved Computational Prediction Model for Lysine Succinylation Sites Mapping on Homo sapiens by Fusing Three Sequence Encoding Schemes with the Random Forest Classifier
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DOI: 10.2174/1389202922666210219114211
Abstract: Background Lysine succinylation is one of the reversible protein post-translational modifications (PTMs), which regulate the structure and function of proteins. It plays a significant role in various cellular physiologies including some diseases of human as… read more here.
Keywords: succinylation; succinylation sites; lysine succinylation; sites mapping ... See more keywords
Deep_KsuccSite: A novel deep learning method for the identification of lysine succinylation sites
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DOI: 10.3389/fgene.2022.1007618
Abstract: Identification of lysine (symbol Lys or K) succinylation (Ksucc) sites centralizes the basis for disclosing the mechanism and function of lysine succinylation modifications. Traditional experimental methods for Ksucc site ientification are often costly and time-consuming.… read more here.
Keywords: ksuccsite; deep ksuccsite; identification; deep learning ... See more keywords
The analysis of lysine succinylation modification reveals the mechanism of oxybenzone damaging of pakchoi (Brassica rapa L. ssp. chinensis)
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2022.1001935
Abstract: Oxybenzone (OBZ), one of a broad spectrum of ultraviolet (UV) absorbents, has been proven to be harmful to both plants and animals, while omics analysis of big data at the molecular level is still lacking.… read more here.
Keywords: pakchoi; modification; analysis lysine; lysine succinylation ... See more keywords