A No-Lysis Flow Cytometry Protocol to Characterize Heterotypic Aggregates with Red Blood Cells in Sickle Cell Disease
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DOI: 10.1152/physiol.2023.38.s1.5734374
Abstract: Sickle Cell Disease (SCD) is an inherited hemoglobinopathy characterized by a pro-inflammatory, pro-thrombotic phenotype. Platelet-leukocyte aggregates (PLAs), a hallmark of thrombo-inflammatory diseases, are elevated in SCD. While neutrophils play a role in aggregate formation, little… read more here.
Keywords: lysis protocol; scd mice; lysis; physiology ... See more keywords