Articles with "lysosomal acidification" as a keyword



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Tubulin deacetylase NDST3 modulates lysosomal acidification: Implications in neurological diseases

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Published in 2022 at "BioEssays"

DOI: 10.1002/bies.202200110

Abstract: Neurological diseases (NDs), featured by progressive dysfunctions of the nervous system, have become a growing burden for the aging populations. N‐Deacetylase and N‐sulfotransferase 3 (NDST3) is known to catalyze deacetylation and N‐sulfation on disaccharide substrates.… read more here.

Keywords: neurological diseases; lysosomal acidification; deacetylase; tubulin deacetylase ... See more keywords
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Roles for H+/K+‐ATPase and zinc transporter 3 in cAMP‐mediated lysosomal acidification in bafilomycin A1‐treated astrocytes

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Published in 2020 at "Glia"

DOI: 10.1002/glia.23952

Abstract: Vacuolar ATPase (v‐ATPase) is the main proton pump that acidifies vesicles such as lysosomes. Disruption in the lysosomal localization of v‐ATPase leads to lysosomal dysfunction, thus contributing to the pathogenesis of lysosomal storage disorders and… read more here.

Keywords: camp; atpase; mediated lysosomal; camp mediated ... See more keywords