MicroRNA-1-3p Suppresses Malignant Phenotypes of Ameloblastoma Through Down-Regulating Lysosomal Associated Membrane Protein 2-Mediated Autophagy
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DOI: 10.3389/fmed.2021.670188
Abstract: Objective: Several clinical trials have suggested that autophagy inhibition is a promising approach for cancer therapy. However, the implications of autophagy in ameloblastoma (AB) remain undiscovered. This study investigated the dysregulated autophagy and its regulatory… read more here.
Keywords: protein; mediated autophagy; lysosomal associated; associated membrane ... See more keywords
Lysosomal-associated transmembrane protein 5 deficiency exacerbates cerebral ischemia/reperfusion injury
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2022.971361
Abstract: Lysosomal-associated transmembrane protein 5 (LAPTM5) has been demonstrated to be involved in regulating immunity, inflammation, cell death, and autophagy in the pathophysiological processes of many diseases. However, the function of LAPTM5 in cerebral ischemia-reperfusion (I/R)… read more here.
Keywords: cerebral ischemia; transmembrane protein; lysosomal associated; associated transmembrane ... See more keywords