The Novel Lysosomal Autophagy Inhibitor (ROC-325) Ameliorates Experimental Pulmonary Hypertension
Sign Up to like & getrecommendations! Published in 2022 at "Hypertension"
DOI: 10.1161/hypertensionaha.122.19397
Abstract: Background: Autophagy plays an important role in the pathogenesis of pulmonary hypertension (PH). ROC-325 is a novel small molecule lysosomal autophagy inhibitor that has more potent anticancer activity than the antimalarial drug hydroxychloroquine, the latter… read more here.
Keywords: roc 325; pulmonary hypertension; lysosomal autophagy; nitric oxide ... See more keywords
Endo-Lysosomal and Autophagy Pathway and Ubiquitin-Proteasome System in Mood Disorders: A Review Article
Sign Up to like & getrecommendations! Published in 2023 at "Neuropsychiatric Disease and Treatment"
DOI: 10.2147/ndt.s376380
Abstract: Abstract Mood disorders are disabling conditions that cause significant functional impairment. Due to the clinical heterogeneity and complex nature of these disorders, diagnostic and treatment strategies face challenges. The etiology of mood disorders is multifactorial,… read more here.
Keywords: system; endo lysosomal; lysosomal autophagy; autophagy pathway ... See more keywords