Multi-omic approach characterises the neuroprotective role of retromer in regulating lysosomal health
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DOI: 10.1101/2022.09.13.507260
Abstract: Retromer controls cellular homeostasis through regulating integral membrane protein sorting and transport and by controlling late-stage maturation of the endo-lysosomal network. Retromer dysfunction, which is linked to neurodegenerative disorders including Parkinson’s and Alzheimer’s diseases, manifests… read more here.
Keywords: retromer; regulating lysosomal; dysfunction; lysosomal health ... See more keywords