Fatty Acid Synthase (FASN) Maintains Leukemogenesis By Suppressing Progranulin-Engaged Lysosomal and Inflammatory Signaling
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DOI: 10.1182/blood-2024-200731
Abstract: Cancer cells rely on lipogenesis in addition to the exogenous lipid up-taking, in which the lipogenic enzyme fatty acid synthase has aberrant over-expression in various cancers, including myeloid leukemia. However, the precise role of FASN… read more here.
Keywords: lysosomal inflammatory; acid synthase; fasn; cell ... See more keywords