Articles with "lysosome mediated" as a keyword



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Potent half-sandwich Ru(Ⅱ) N^N (aryl-BIAN) complexes: Lysosome-mediated apoptosis, in vitro and in vivo anticancer activities.

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Published in 2020 at "European journal of medicinal chemistry"

DOI: 10.1016/j.ejmech.2020.112763

Abstract: Herein a new series of organometallic half-sandwich Ru(Ⅱ) complexes bearing aryl-BIAN chelating ligands with various electron-withdrawing and electron-donating substituents have been developed as theranostic agents. All the complexes display much higher anti-proliferative potency than the… read more here.

Keywords: lysosome mediated; aryl bian; apoptosis vitro; apoptosis ... See more keywords