Simultaneous Single-particle Tracking and Dynamic pH Sensing Reveal Lysosome-targetable Mesoporous Silica Nanoparticles Pathways.
Sign Up to like & getrecommendations! Published in 2020 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.0c07917
Abstract: Nanoparticles (NPs)-based targeted drug delivery is intended to transport therapeutically active molecules to specific cells, and particular intracellular compartments. However, there is limited knowledge regarding the complete route of NPs in this targeting scenario. In… read more here.
Keywords: lysosome targetable; mesoporous silica; silica nanoparticles; particle tracking ... See more keywords
A Lysosome-Targetable Fluorescent Probe for Simultaneously Sensing Cys/Hcy, GSH, and H2S from Different Signal Patterns.
Sign Up to like & getrecommendations! Published in 2018 at "ACS sensors"
DOI: 10.1021/acssensors.8b01101
Abstract: Biothiols, a vital branch of reactive sulfur species (RSS) family, are indispensable in human physiology. However, the exact functional roles of each biothiol involved in complicated physiological activities are still not fully clarified. A critical… read more here.
Keywords: lysosome targetable; signal patterns; cys hcy; hcy gsh ... See more keywords
Rational design of ratiometric and lysosome-targetable AIE dots for imaging endogenous HClO in live cells
Sign Up to like & getrecommendations! Published in 2019 at "Materials Chemistry Frontiers"
DOI: 10.1039/c8qm00511g
Abstract: A novel lysosome-targetable ratiometric AIE nanoprobe was rationally designed and synthesized for sensing of endogenous HClO levels in live cells. read more here.
Keywords: rational design; endogenous hclo; ratiometric lysosome; lysosome targetable ... See more keywords
A Multifunctional and Fast-Response Lysosome-Targetable Fluorescent Probe for Monitoring pH and Isoxaflutole
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23116256
Abstract: A new chemosensor, namely N-(2-morpholinoethyl)acetamide-4-morpholine-1,8-naphthimide (MMN), was designed and synthesized through an amidation reaction. MMN was fabricated as a multifunctional fluorescent probe for monitoring pH and isoxaflutole. MMN exhibited excellent stability in MeCN/H2O (v/v, 9/1),… read more here.
Keywords: probe monitoring; lysosome targetable; mmn; monitoring isoxaflutole ... See more keywords