A novel LysR‐type regulator negatively affects biosynthesis of the immunosuppressant brasilicardin
Sign Up to like & getrecommendations! Published in 2021 at "Engineering in Life Sciences"
DOI: 10.1002/elsc.202000038
Abstract: Brasilicardin A (BraA) is a promising immunosuppressive compound produced naturally by the pathogenic bacterium Nocardia terpenica IFM 0406. Heterologous host expression of brasilicardin gene cluster showed to be efficient to bypass the safety issues, low… read more here.
Keywords: bra bgc; brasilicardin; lysr type; gene ... See more keywords
Determination of the regulatory network and function of the lysR-type transcriptional regulator of Lactiplantibacillus plantarum, LpLttR
Sign Up to like & getrecommendations! Published in 2022 at "Microbial Cell Factories"
DOI: 10.1186/s12934-022-01774-9
Abstract: Background Lactiplantibacillus plantarum has various healthcare functions including the regulation of immunity and inflammation, reduction of serum cholesterol levels, anti-tumor activity, and maintenance of the balance of intestinal flora. However, the underlying metabolic and regulatory… read more here.
Keywords: regulatory network; lactiplantibacillus plantarum; plantarum; type transcriptional ... See more keywords
STRUCTURAL STUDIES OF TRANSCRIPTIONAL REGULATION BY LysR-TYPE TRANSCRIPTIONAL REGULATORS IN BACTERIA
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DOI: 10.7831/ras.6.105-118
Abstract: LysR-type transcriptional regulators (LTTRs) comprise one of the largest families of transcriptional regulators in bacteria and control gene expression of various types of metabolic, virulence and physiological functions. LTTRs typically form homotetramers and require an… read more here.
Keywords: regulators bacteria; transcriptional regulators; helix; lysr type ... See more keywords