Articles with "lyssavirus" as a keyword



The matrix protein of lyssavirus hijacks autophagosome for efficient egress by recruiting NEDD4 through its PPxY motif

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Published in 2024 at "Autophagy"

DOI: 10.1080/15548627.2024.2338575

Abstract: ABSTRACT Lyssaviruses are well-known worldwide and often cause fatal encephalitis. Previous studies have shown that autophagy is beneficial for the replication of rabies virus (RABV), the representative lyssavirus, but the detailed mechanism remains obscure. In… read more here.

Keywords: ppxy motif; matrix protein; lyssavirus; protein ... See more keywords

Substitution of S179P in the Lyssavirus Phosphoprotein Impairs Its Interferon Antagonistic Function

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Published in 2022 at "Journal of Virology"

DOI: 10.1128/jvi.01125-22

Abstract: Interferon (IFN) and the IFN-induced cellular antiviral response constitute the first line of defense against viral invasion. Evading host innate immunity, especially IFN signaling, is the key step required for lyssaviruses to establish infection. ABSTRACT… read more here.

Keywords: function; substitution; lyssavirus phosphoprotein; lyssavirus ... See more keywords

Lyssavirus M protein degrades neuronal microtubules by reprogramming mitochondrial metabolism

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Published in 2024 at "mBio"

DOI: 10.1128/mbio.02880-23

Abstract: ABSTRACT Infection with neurotropic viruses may result in changes in host behavior, which are closely associated with degenerative changes in neurons. The lyssavirus genus comprises highly neurotropic viruses, including the rabies virus (RABV), which has… read more here.

Keywords: mitochondrial metabolism; lyssavirus; protein; infection ... See more keywords

A Preliminary Study on Bat Lyssavirus in Assam, India

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Published in 2024 at "Indian Journal of Animal Research"

DOI: 10.18805/ijar.b-5258

Abstract: Background: Rabies is a zoonotic disease caused by Lyssavirus of the family Rhabdoviridae, affecting all warm-blooded animals. Although a vast majority of the cases are canine-mediated, many cases of bat-mediated rabies in humans have been… read more here.

Keywords: lyssavirus assam; bat lyssavirus; lyssavirus; bat ... See more keywords

Taiwan Bat Lyssavirus: In Vitro and In Vivo Assessment of the Ability of Rabies Vaccine-Derived Antibodies to Neutralise a Novel Lyssavirus

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Published in 2022 at "Viruses"

DOI: 10.3390/v14122750

Abstract: Rabies is a neglected tropical disease. The prototype virus, the rabies virus, still causes tens of thousands of human fatalities annually. Rabies is one member of the genus Lyssavirus. The burden of other lyssaviruses is… read more here.

Keywords: bat lyssavirus; lyssavirus; taiwan bat; sera ... See more keywords

Comparison of Pan-Lyssavirus RT-PCRs and Development of an Improved Protocol for Surveillance of Non-RABV Lyssaviruses

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Published in 2023 at "Viruses"

DOI: 10.3390/v15030680

Abstract: Rabies is a zoonotic and fatal encephalitis caused by members of the Lyssavirus genus. Among them, the most relevant species is Lyssavirus rabies, which is estimated to cause 60,000 human and most mammal rabies deaths… read more here.

Keywords: comparison pan; surveillance; lyssavirus; lyssavirus pcrs ... See more keywords