The yeast LYST homolog Bph1 is a Rab5 effector and prevents Atg8 lipidation at endosomes.
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DOI: 10.1242/jcs.259421
Abstract: Lysosomes mediate degradation of macromolecules to their precursors for their cellular recycling. Additionally, lysosome-related organelles mediate cell type-specific functions. The Chédiak-Higashi syndrome is an autosomal, recessive disease, in which loss of the protein LYST causes… read more here.
Keywords: rab5; bph1; lyst homolog; homolog bph1 ... See more keywords