Enhancement of Lytic Activity by Leptin Is Independent From Lipid Rafts in Murine Primary Splenocytes
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.25394
Abstract: Leptin, a pleiotropic adipokine, is known as a regulator of food intake, but it is also involved in inflammation, immunity, cell proliferation, and survival. Leptin receptor is integrated inside cholesterol‐rich microdomains called lipid rafts, which,… read more here.
Keywords: lytic activity; lipid rafts; leptin; membrane remodeling ... See more keywords
PhageScore: A simple method for comparative evaluation of bacteriophages lytic activity
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical Engineering Journal"
DOI: 10.1016/j.bej.2020.107652
Abstract: Abstract Nowadays, an increasing amount of studies indicate the numerous applications of bacteriophages (e.g. medical, pharmaceutical, use in animal breeding, food processing). However, so far, there is limited availability of simple, efficient, and sensitive methods… read more here.
Keywords: lytic activity; comparative evaluation; activity; method comparative ... See more keywords
The effect of pH on the lytic activity of a synthetic mastoparan-like peptide in anionic model membranes.
Sign Up to like & getrecommendations! Published in 2018 at "Chemistry and physics of lipids"
DOI: 10.1016/j.chemphyslip.2018.09.005
Abstract: Peptide sequences containing acidic and basic residues could potentially have their net charges modulated by bulk pH with a possible influence on their lytic activity in lipid vesicles. The present study reports on a biophysical… read more here.
Keywords: synthetic mastoparan; mastoparan like; lytic activity; activity ... See more keywords
Identification and Molecular Modification of Staphylococcus aureus Bacteriophage Lysin LysDZ25.
Sign Up to like & getrecommendations! Published in 2023 at "ACS infectious diseases"
DOI: 10.1021/acsinfecdis.2c00493
Abstract: With the continuous emergence and spread of drug-resistant and multi-drug-resistant Staphylococcus aureus, traditional antibiotic treatment has gradually lost its effect. There is an urgent need to develop and study new and effective bio-green inhibitors to… read more here.
Keywords: staphylococcus aureus; lysin lysdz25; lytic activity; lysdz25 ... See more keywords
LIPIODOL reduces the lytic activity of detergent sclerosants in vitro.
Sign Up to like & getrecommendations! Published in 2021 at "Phlebology"
DOI: 10.1177/02683555211018312
Abstract: OBJECTIVES Contrast agents are used widely in the interventional setting and in particularly in the management of vascular anomalies and have also been used in combination with sclero-embolic agents. There is limited information on the… read more here.
Keywords: contrast agents; detergent; detergent sclerosants; lytic activity ... See more keywords
Isolation and characterization of bacteriophages with lytic activity against common bacterial pathogens
Sign Up to like & getrecommendations! Published in 2017 at "Veterinary World"
DOI: 10.14202/vetworld.2017.973-978
Abstract: Aim: Present investigation was conducted to isolate and characterize bacteriophages with lytic activity against common bacterial pathogens. Materials and Methods: A total of 60 samples of animal waste disposal from cattle (42) and buffalo (18)… read more here.
Keywords: bacteriophages lytic; lytic activity; phage; common bacterial ... See more keywords
Characterization and Lytic Activity of Isolated Escherichia coli Bacteriophages against Escherichia coli in vitro
Sign Up to like & getrecommendations! Published in 2020 at "Iranian Journal of Medical Sciences"
DOI: 10.30476/ijms.2019.45420
Abstract: Background: Escherichia coli (E. coli) is the most common cause of urinary tract infection (UTI) and typically treated with antibiotics. Unrestricted use of antibiotics may lead to the emergence of antibiotic-resistant bacteria. The present study… read more here.
Keywords: microscopy; escherichia coli; lytic activity; urine samples ... See more keywords
Lytic Activity of Polyvalent Staphylococcal Bacteriophage PhiSA012 and Its Endolysin Lys-PhiSA012 Against Antibiotic-Resistant Staphylococcal Clinical Isolates From Canine Skin Infection Sites
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2020.00234
Abstract: The spread of antibiotic-resistant bacteria (ARB) in human and veterinary medicine is of global concern. Notably, the emergence of methicillin-resistant Staphylococcus pseudintermedius has become a serious problem. In this context, bacteriophages and their lytic enzymes,… read more here.
Keywords: lytic activity; phisa012; lys phisa012; canine skin ... See more keywords
The Novel Enterococcus Phage vB_EfaS_HEf13 Has Broad Lytic Activity Against Clinical Isolates of Enterococcus faecalis
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2019.02877
Abstract: Enterococcus faecalis is a Gram-positive, facultative anaerobic bacterium frequently found in the gastrointestinal tract, oral cavity, and periodontal tissue. Although it is considered a commensal, it can cause bacteremia, endocarditis, endodontic infections, and urinary tract… read more here.
Keywords: lytic activity; phage; phage hef13; clinical isolates ... See more keywords
Development of a Novel Chimeric Endolysin, Lys109 With Enhanced Lytic Activity Against Staphylococcus aureus
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2020.615887
Abstract: As the incidence of antibiotic-resistant bacteria has become increased, phage endolysins are believed as one of the promising alternatives to antibiotics. However, the discovery of potent endolysin is still challenging because it is labor intensive… read more here.
Keywords: chimeric endolysin; lys109; lytic activity; novel chimeric ... See more keywords
Biochemical Characterizations of the Putative Endolysin Ecd09610 Catalytic Domain from Clostridioides difficile
Sign Up to like & getrecommendations! Published in 2022 at "Antibiotics"
DOI: 10.3390/antibiotics11081131
Abstract: Clostridioides difficile is the major pathogen of pseudomembranous colitis, and novel antimicrobial agents are sought after for its treatment. Phage-derived endolysins with species-specific lytic activity have potential as novel antimicrobial agents. We surveyed the genome… read more here.
Keywords: endolysin; clostridioides difficile; domain variants; domain ... See more keywords