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   Articles with "lytic induction" as a keyword



Selective oncolytic effect in Epstein-Barr virus (EBV)-associated gastric carcinoma through efficient lytic induction by Euphorbia extracts

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recommendations! Published in 2018 at "Journal of Functional Foods"

DOI: 10.1016/j.jff.2018.01.004

Abstract: Abstract Lytic induction of latent Epstein-Barr virus (EBV) has been considered as a therapeutic approach for efficient treatment of EBV-associated malignancies. Here, we established a robust assay system quantitatively measuring EBV lytic induction and identified… read more here.

Keywords: gastric carcinoma; ebv; ebv associated; lytic induction ... See more keywords

PD-L1 upregulation by lytic induction of Epstein-Barr Virus.

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recommendations! Published in 2022 at "Virology"

DOI: 10.1016/j.virol.2022.01.006

Abstract: Epstein-Barr virus (EBV) is an etiologic agent of infectious mononucleosis and several malignancies. Here, we found that reactivation of EBV resulted in increased programmed cell death-ligand 1 (PD-L1) expression in a cell type-dependent manner. Lytic… read more here.

Keywords: lytic induction; cell; barr virus; epstein barr ... See more keywords

Characterizing resistant cellular states in nasopharyngeal carcinoma during EBV lytic induction

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recommendations! Published in 2025 at "Oncogene"

DOI: 10.1038/s41388-025-03341-z

Abstract: The pervasive occurrence of nasopharyngeal carcinoma (NPC) is intricately linked to Epstein–Barr virus (EBV) infection, making EBV and its associated pathways promising therapeutic targets for NPC and other EBV-related cancers. Lytic induction therapy, an emerging… read more here.

Keywords: ebv lytic; ebv associated; lytic induction; nasopharyngeal carcinoma ... See more keywords

Curcumin derivative C210 induces Epstein–Barr virus lytic cycle and inhibits virion production by disrupting Hsp90 function

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recommendations! Published in 2024 at "Scientific Reports"

DOI: 10.1038/s41598-024-77294-w

Abstract: Lytic induction therapy was devised to selectively combat malignancies associated with Epstein–Barr virus (EBV) by triggering viral reactivation from latency. At present, the major challenges of lytic induction therapy are to maximize reactivating efficiencies and… read more here.

Keywords: epstein barr; lytic induction; c210; virion ... See more keywords

Drug Modulators of B Cell Signaling Pathways and Epstein-Barr Virus Lytic Activation

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recommendations! Published in 2017 at "Journal of Virology"

DOI: 10.1128/jvi.00747-17

Abstract: ABSTRACT Epstein-Barr virus (EBV) is a ubiquitous human gammaherpesvirus that establishes a latency reservoir in B cells. In this work, we show that ibrutinib, idelalisib, and dasatinib, drugs that block B cell receptor (BCR) signaling… read more here.

Keywords: epstein barr; lytic induction; barr virus; activation ... See more keywords