Selective oncolytic effect in Epstein-Barr virus (EBV)-associated gastric carcinoma through efficient lytic induction by Euphorbia extracts
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Functional Foods"
DOI: 10.1016/j.jff.2018.01.004
Abstract: Abstract Lytic induction of latent Epstein-Barr virus (EBV) has been considered as a therapeutic approach for efficient treatment of EBV-associated malignancies. Here, we established a robust assay system quantitatively measuring EBV lytic induction and identified… read more here.
Keywords: gastric carcinoma; ebv; ebv associated; lytic induction ... See more keywords
PD-L1 upregulation by lytic induction of Epstein-Barr Virus.
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DOI: 10.1016/j.virol.2022.01.006
Abstract: Epstein-Barr virus (EBV) is an etiologic agent of infectious mononucleosis and several malignancies. Here, we found that reactivation of EBV resulted in increased programmed cell death-ligand 1 (PD-L1) expression in a cell type-dependent manner. Lytic… read more here.
Keywords: lytic induction; cell; barr virus; epstein barr ... See more keywords
Drug Modulators of B Cell Signaling Pathways and Epstein-Barr Virus Lytic Activation
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DOI: 10.1128/jvi.00747-17
Abstract: ABSTRACT Epstein-Barr virus (EBV) is a ubiquitous human gammaherpesvirus that establishes a latency reservoir in B cells. In this work, we show that ibrutinib, idelalisib, and dasatinib, drugs that block B cell receptor (BCR) signaling… read more here.
Keywords: epstein barr; lytic induction; barr virus; activation ... See more keywords