Abstract CT271: Translational analyses of ATR inhibitor M1774 in a Phase I study in patients with solid tumors (DDRiver Solid Tumors 301)
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DOI: 10.1158/1538-7445.am2023-ct271
Abstract: Background: Ataxia telangiectasia and Rad3-related (ATR) protein kinase plays a critical role in the DNA damage response. M1774, a potent, selective, orally administered ATR inhibitor with antitumor activity in preclinical models, was evaluated as monotherapy… read more here.
Keywords: m1774; atr inhibitor; inhibitor; solid tumors ... See more keywords