Tadalafil Rescues the p.M325T Mutant of Best1 Chloride Channel
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DOI: 10.3390/molecules28083317
Abstract: Bestrophin 1 (Best1) is a chloride channel that localises to the plasma membrane of retinal pigment epithelium (RPE) cells. Mutations in the BEST1 gene are associated with a group of untreatable inherited retinal dystrophies (IRDs)… read more here.
Keywords: mutant best1; chloride channel; m325t mutant; best1 chloride ... See more keywords