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Published in 2020 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2020.173021
Abstract: Morphine-3-glucuronide (M3G), the main metabolite of morphine, has been implicated in the development of tolerance and of opioid-induced hyperalgesia, both limiting the analgesic use of morphine. We evaluated the acute and chronic effects of M3G…
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Keywords:
substance;
antinociceptive cross;
cross tolerance;
m3g ... See more keywords