The PET tracer [11C]MK-6884 quantifies M4 muscarinic receptor in rhesus monkeys and patients with Alzheimer’s disease
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DOI: 10.1126/scitranslmed.abg3684
Abstract: Description [11C]MK-6884 is an M4R-specific PET tracer for quantifying target engagement in brain and providing insights into AD neuropathology. Quantifying M4R engagement Activation of the M4 muscarinic receptor (M4R) might be therapeutic in patients with… read more here.
Keywords: target engagement; 11c 6884; m4r; pet tracer ... See more keywords