5-methylcytosine (m5C) RNA modification controls the innate immune response to virus infection by regulating type I interferons
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2123338119
Abstract: Significance 5-methylcytosine (m5C) is a common RNA methylation. However, its biological functions remain a mystery. Here, we discover that depletion of NSUN2, an m5C methyltransferase, leads to an enhanced type I interferon (IFN) response, which… read more here.
Keywords: rna modification; m5c rna; rna; methylcytosine m5c ... See more keywords
Prognostic Value of an m5C RNA Methylation Regulator-Related Signature for Clear Cell Renal Cell Carcinoma
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DOI: 10.2147/cmar.s323072
Abstract: Purpose Clear cell renal cell carcinoma (ccRCC) is highly heterogeneous and is one of the most lethal types of cancer within the urinary system. Aberrant expression of 5-methylcytosine (m5C) RNA methylation regulators has been shown… read more here.
Keywords: m5c rna; signature; cell; ccrcc ... See more keywords
Overall Survival Signature of 5-Methylcytosine Regulators Related Long Non-Coding RNA in Hepatocellular Carcinoma
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DOI: 10.3389/fonc.2022.884377
Abstract: Purpose Studies reported that 5-methylcytosine (m5C) RNA transferase alters tumor progression; however, studies of m5C-related lncRNA remain lacking. This article intends to study the lncRNA modified by m5C RNA transferase in hepatocellular carcinoma using a… read more here.
Keywords: hepatocellular carcinoma; m5c rna; rna transferase; transferase ... See more keywords