Synaptic N6-methyladenosine (m6A) epitranscriptome reveals functional partitioning of localized transcripts
Sign Up to like & getrecommendations! Published in 2018 at "Nature Neuroscience"
DOI: 10.1038/s41593-018-0173-6
Abstract: A localized transcriptome at the synapse facilitates synapse-, stimulus- and transcript-specific local protein synthesis in response to neuronal activity. While enzyme-mediated mRNA modifications are known to regulate cellular mRNA turnover, the role of these modifications… read more here.
Keywords: methyladenosine m6a; synaptic methyladenosine; m6a epitranscriptome; m6a ... See more keywords
Interplay between the m6A Epitranscriptome and Tumor Metabolism: Mechanisms and Therapeutic Implications
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10102589
Abstract: N6-methyladenosine (m6A) modification of messenger RNA (mRNA) influences the stability and translation of the transcripts into functional proteins. Recent studies reveal the role of m6A modifications in regulating the metabolism of basic biomolecules such as… read more here.
Keywords: metabolism; m6a epitranscriptome; therapeutic implications; interplay m6a ... See more keywords