RNA methylation-related genes of m6A, m5C, and m1A predict prognosis and immunotherapy response in cervical cancer
Sign Up to like & getrecommendations! Published in 2023 at "Annals of Medicine"
DOI: 10.1080/07853890.2023.2190618
Abstract: Abstract Purpose To investigate the prognostic value of N6-methyladenosine (m6A)-, 5-methylcytosine (m5C)-, and N1-methyladenosine (m1A)-related genes in cervical cancer (CESC) and predicting immunotherapy response. Methods We downloaded cervical cancer mRNA expression profiles, clinical data, and… read more here.
Keywords: cervical cancer; methylation; m6a m5c; m5c m1a ... See more keywords
Cross-Talk Between m6A- and m5C-Related lncRNAs to Construct a Novel Signature and Predict the Immune Landscape of Colorectal Cancer Patients
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DOI: 10.3389/fimmu.2022.740960
Abstract: Background N6-methyladenosine (m6A) and 5-methylcytosine (m5C) can modify long non-coding RNAs (lncRNAs), thereby affecting tumorigenesis and tumor progression. However, there is a lack of knowledge regarding the potential roles and cross-talk of m6A- and m5C-related… read more here.
Keywords: signature; related lncrnas; m6a m5c; m5c related ... See more keywords
Comprehensive analysis of m6A/m5C/m1A-related gene expression, immune infiltration, and sensitivity of antineoplastic drugs in glioma
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DOI: 10.3389/fimmu.2022.955848
Abstract: This research aims to develop a prognostic glioma marker based on m6A/m5C/m1A genes and investigate the potential role in the tumor immune microenvironment. Data for patients with glioma were downloaded from The Cancer Genome Atlas… read more here.
Keywords: m6a m5c; m5c m1a; expression; analysis ... See more keywords
The lncRNA epigenetics: The significance of m6A and m5C lncRNA modifications in cancer
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DOI: 10.3389/fonc.2023.1063636
Abstract: Most of our transcribed RNAs are represented by non-coding sequences. Long non-coding RNAs (lncRNAs) are transcripts with no or very limited protein coding ability and a length >200nt. They can be epigenetically modified. N6-methyladenosine (m6A),… read more here.
Keywords: m6a m5c; epigenetic modifications; significance; m6a ... See more keywords
Prognostic Value and Genome Signature of m6A/m5C Regulated Genes in Early-Stage Lung Adenocarcinoma
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DOI: 10.3390/ijms24076520
Abstract: RNA modifications implicate pathological and prognosis significance in cancer development and progression, of which, m6A and m5C are representative regulators. These RNA modifications could produce effects on the function of other RNA by regulating gene… read more here.
Keywords: early stage; m6a m5c; expression;