The function of the m6A methyltransferase METTL3 in goat early embryo development under hypoxic and normoxic conditions.
Sign Up to like & getrecommendations! Published in 2021 at "Theriogenology"
DOI: 10.1016/j.theriogenology.2021.10.017
Abstract: It has been reported that N6-methyladenosine (m6A) methyltransferase-like 3 (METTL3) plays an important role in zygote genome activation during embryonic development, but the effects of METTL3 under oxidative stress in the early development of goat… read more here.
Keywords: mettl3; normoxic conditions; m6a methyltransferase; cell ... See more keywords
m6A methyltransferase KIAA1429 acts as an oncogenic factor in colorectal cancer by regulating SIRT1 in an m6A-dependent manner
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DOI: 10.1038/s41420-022-00878-w
Abstract: N6-methyladenosine (m6A) modifications of RNAs are involved in various aspects of colorectal carcinogenesis via regulation of mRNA stability, splicing, and translation. KIAA1429, an m6A methyltransferase, was found deregulated in multiple cancer types. However, its role… read more here.
Keywords: cancer; kiaa1429; colorectal cancer; m6a methyltransferase ... See more keywords
RNA m6A Methyltransferase METTL3 Promotes The Growth Of Prostate Cancer By Regulating Hedgehog Pathway
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DOI: 10.2147/ott.s226796
Abstract: Purpose N6-methyladenosine (m6A) is the most abundant internal modification on eukaryotic mRNA and gained increasing attention recently. More and more evidence suggest that m6A methylation plays crucial role in tumor genesis and development. However, its… read more here.
Keywords: mettl3; m6a methyltransferase; prostate cancer;
m6A Methyltransferase METTL3 Promotes the Progression of Primary Acral Melanoma via Mediating TXNDC5 Methylation
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DOI: 10.3389/fonc.2021.770325
Abstract: m6A modification is one of the most important post-transcriptional modifications in RNA and plays an important role in promoting translation or decay of RNAs. The role of m6A modifications has been highlighted by increasing evidence… read more here.
Keywords: primary acral; mettl3; acral melanoma; melanoma ... See more keywords
Comparative Genomics and Functional Studies of Putative m6A Methyltransferase (METTL) Genes in Cotton
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DOI: 10.3390/ijms232214111
Abstract: N6-methyladenosine (m6A) RNA modification plays important regulatory roles in plant development and adapting to the environment, which requires methyltransferases to achieve the methylation process. However, there has been no research regarding m6A RNA methyltransferases in… read more here.
Keywords: methyltransferase mettl; cotton; m6a methyltransferase; mettl genes ... See more keywords