N6‐methyladenosine regulators are potential prognostic biomarkers for multiple myeloma
Sign Up to like & getrecommendations! Published in 2022 at "IUBMB Life"
DOI: 10.1002/iub.2678
Abstract: N6‐methyladenosine (m6A) regulators play an important role in tumorigenesis; however, their role in multiple myeloma (MM) remains unknown. This study aimed to create an m6A RNA regulators prognostic signature for MM patients. We integrated data… read more here.
Keywords: gene; signature; methyladenosine regulators; m6a regulators ... See more keywords
Expression pattern of m6A regulators is significantly correlated with malignancy and antitumor immune response of breast cancer
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Gene Therapy"
DOI: 10.1038/s41417-020-00208-1
Abstract: More than 24 regulators have been revealed to dynamically participant in N6-methyladenosine (m6A) RNA methylation, and play critical roles in tumorigenesis and development of cancers. However, their functional roles have not been comprehensively clarified in… read more here.
Keywords: breast cancer; m6a regulators; m6a; cancer ... See more keywords
MP09-10 GENETIC ALTERATIONS OF M6A REGULATORS PREDICT POOR SURVIVAL IN PATIENTS WITH PROSTATE CANCER
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Urology"
DOI: 10.1097/ju.0000000000000829.010
Abstract: and P30CA046592 (P.B.) from the National Cancer Institute. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Cancer Institute or the National Institutes of… read more here.
Keywords: m6a regulators; alterations m6a; cancer; mp09 genetic ... See more keywords
Prognostic and therapeutic implication of m6A methylation in Crohn disease
Sign Up to like & getrecommendations! Published in 2022 at "Medicine"
DOI: 10.1097/md.0000000000032399
Abstract: Background: N6-methyladenosine (m6A) methylation has been reported to participate in inflammatory bowel disease (including Crohn disease [CD]). However, the prognostic and therapeutic implication of m6A methylation modification in CD is still unclear. Methods: Genomic information… read more here.
Keywords: m6a methylation; disease; expression; m6a regulators ... See more keywords
Analysis of N6-Methyladenosine RNA Methylation Regulators in Diagnosis and Distinct Molecular Subtypes of Ankylosing Spondylitis
Sign Up to like & getrecommendations! Published in 2022 at "Disease Markers"
DOI: 10.1155/2022/4942599
Abstract: The most frequent internal modification in eukaryotic mRNA is N6-methyladenosine (m6A). However, what we know about the m6A regulators in Ankylosing spondylitis (AS) is still limited. In our study, eight distinct m6A regulators were selected… read more here.
Keywords: m6a; m6a regulators; analysis methyladenosine; ankylosing spondylitis ... See more keywords
Identification of Molecular Subtypes and Potential Small-Molecule Drugs for Esophagus Cancer Treatment Based on m6A Regulators
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Oncology"
DOI: 10.1155/2022/5490461
Abstract: Background Esophagus cancer (ESCA) is the sixth most frequent cancer in males, with 5-year overall survival of 15%–25%. RNA modifications function critically in cancer progression, and m6A regulators are associated with ESCA prognosis. This study… read more here.
Keywords: molecular subtypes; m6a regulators; esophagus cancer; cancer ... See more keywords
N6-methyladenosine (m6A) RNA modification in the pathophysiology of heart failure: a narrative review
Sign Up to like & getrecommendations! Published in 2022 at "Cardiovascular Diagnosis and Therapy"
DOI: 10.21037/cdt-22-277
Abstract: Background and Objective Heart failure is the end-stage of various cardiovascular diseases. Recent progress in molecular biology has facilitated the understanding of the mechanisms of heart failure development at the molecular level. N6-adenosine methylation (m6A)… read more here.
Keywords: modification; heart failure; m6a regulators; heart ... See more keywords
Molecular Characteristics of m6A Regulators and Tumor Microenvironment Infiltration in Soft Tissue Sarcoma: A Gene-Based Study
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2022.846812
Abstract: Background: N6-methyladenosine (m6A) methylation played a key role in tumor growth. However, the relationship between m6A and soft tissue sarcoma (STS) was still unclear. Methods: The characterization and patterns of m6A modification in STS (TCGA-SARC… read more here.
Keywords: sarcoma; soft tissue; tissue sarcoma; tumor microenvironment ... See more keywords
Comprehensive analysis of the m6A-related molecular patterns and diagnostic biomarkers in osteoporosis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.957742
Abstract: Background N6-methyladenosine (m6A) modification is a critical epigenetic modification in eukaryotes and involves several biological processes and occurrences of diseases. However, the roles and regulatory mechanisms of m6A regulators in osteoporosis (OP) remain unclear. Thus,… read more here.
Keywords: network; m6a related; expression; m6a regulators ... See more keywords
RNA N6-Methyladenosine Regulators Contribute to Tumor Immune Microenvironment and Have Clinical Prognostic Impact in Breast Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2021.650499
Abstract: Purpose: This study aims to reveal the relationship between RNA N6-methyladenosine (m6A) regulators and tumor immune microenvironment (TME) in breast cancer, and to establish a risk model for predicting the occurrence and development of tumors.… read more here.
Keywords: immune microenvironment; tumor immune; breast cancer; m6a regulators ... See more keywords
Diagnostic signature, subtype classification, and immune infiltration of key m6A regulators in osteomyelitis patients
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.1044264
Abstract: Background: As a recurrent inflammatory bone disease, the treatment of osteomyelitis is always a tricky problem in orthopaedics. N6-methyladenosine (m6A) regulators play significant roles in immune and inflammatory responses. Nevertheless, the function of m6A modification… read more here.
Keywords: immune infiltration; osteomyelitis; key m6a; m6a regulators ... See more keywords