Articles with "m6a sites" as a keyword



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RFAthM6A: a new tool for predicting m6A sites in Arabidopsis thaliana

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Published in 2018 at "Plant Molecular Biology"

DOI: 10.1007/s11103-018-0698-9

Abstract: Key messageWe curated a reliable dataset of m6A sites in Arabidopsis thaliana, built competitive models for predicting m6A sites, extracted predominant rules from the prediction models and analyzed the most important features.AbstractIn biological RNA, approximately… read more here.

Keywords: new tool; m6a sites; arabidopsis thaliana; predicting m6a ... See more keywords
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m6A-Finder: Detecting m6A methylation sites from RNA transcriptomes using physical and statistical properties based features.

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Published in 2022 at "Computational biology and chemistry"

DOI: 10.1016/j.compbiolchem.2022.107640

Abstract: N6-methyladenosine (m6A) is one of the abundant post-transcription modification in cellular RNA. It regulates different biological processes, such as, protein synthesis, X-chromosome inactivation, cell stability, cell-reprogramming and miRNA regulation etc. Most recently, various studies claimed… read more here.

Keywords: detecting m6a; m6a sites; m6a; properties based ... See more keywords
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Identifying N6-methyladenosine sites using multi-interval nucleotide pair position specificity and support vector machine

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Published in 2017 at "Scientific Reports"

DOI: 10.1038/srep46757

Abstract: N6-methyladenosine (m6A) refers to methylation of the adenosine nucleotide acid at the nitrogen-6 position. It plays an important role in a series of biological processes, such as splicing events, mRNA exporting, nascent mRNA synthesis, nuclear… read more here.

Keywords: interval nucleotide; m6a sites; position; multi interval ... See more keywords
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Deep and accurate detection of m6A RNA modifications using miCLIP2 and m6Aboost machine learning

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Published in 2021 at "Nucleic Acids Research"

DOI: 10.1093/nar/gkab485

Abstract: Abstract N6-methyladenosine (m6A) is the most abundant internal RNA modification in eukaryotic mRNAs and influences many aspects of RNA processing. miCLIP (m6A individual-nucleotide resolution UV crosslinking and immunoprecipitation) is an antibody-based approach to map m6A… read more here.

Keywords: detection; machine learning; m6a sites; rna ... See more keywords
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ELMo4m6A: A Contextual Language Embedding-Based Predictor for Detecting RNA N6-Methyladenosine Sites

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Published in 2022 at "IEEE/ACM Transactions on Computational Biology and Bioinformatics"

DOI: 10.1109/tcbb.2022.3173323

Abstract: N6-methyladenosine (m6A) is a universal post-transcriptional modification of RNAs, and it is widely involved in various biological processes. Identifying m6A modification sites accurately is indispensable to further investigate m6A-mediated biological functions. How to better represent… read more here.

Keywords: contextual language; m6a sites; m6a; elmo4m6a contextual ... See more keywords
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M6A-BERT-Stacking: A Tissue-Specific Predictor for Identifying RNA N6-Methyladenosine Sites Based on BERT and Stacking Strategy

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Published in 2023 at "Symmetry"

DOI: 10.3390/sym15030731

Abstract: As the most abundant RNA methylation modification, N6-methyladenosine (m6A) could regulate asymmetric and symmetric division of hematopoietic stem cells and play an important role in various diseases. Therefore, the precise identification of m6A sites around… read more here.

Keywords: m6a sites; bert stacking; stacking strategy; m6a bert ... See more keywords