IGF2BP3 promotes mRNA degradation through internal m7G modification
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DOI: 10.1038/s41467-024-51634-w
Abstract: Recent studies have suggested that mRNA internal m7G and its writer protein METTL1 are closely related to cell metabolism and cancer regulation. Here, we identify that IGF2BP family proteins IGF2BP1-3 can preferentially bind internal mRNA… read more here.
Keywords: cancer; m7g; degradation; m7g modification ... See more keywords
Integrated analysis from multi-center studies identities m7G-derived modification pattern and risk stratification system in skin cutaneous melanoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1034516
Abstract: The m7G modification has been proven to play an important role in RNA post-transcriptional modification and protein translation. However, the potential role of m7G modification patterns in assessing the prognosis of Skin cutaneous melanoma (SKCM)… read more here.
Keywords: modification; skin cutaneous; m7g modification; cutaneous melanoma ... See more keywords
Overexpression of tRNA m7G modification methyltransferase complex promotes the biosynthesis of triterpene in yeast
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2025.1557443
Abstract: Background The sustainable production of valuable compounds using microbial cell factories is an effective approach, yet further metabolic engineering strategies are needed to enhance their biosynthetic potential. Recent studies suggest that RNA modifications can influence… read more here.
Keywords: biosynthesis; trna m7g; m7g modification; production ... See more keywords