CRISPR Interference-Based Inhibition of MAB_0055c Expression Alters Drug Sensitivity in Mycobacterium abscessus
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DOI: 10.1128/spectrum.00631-23
Abstract: In this study, we utilized CRISPR interference (CRISPRi) to specifically target the MAB_0055c gene in M. abscessus, a bacterium that causes difficult-to-treat infections. The study found that silencing the gene lead to increased rifabutin and… read more here.
Keywords: gene; mab 0055c; crispr interference; abscessus ... See more keywords