Nasal administration of anti-CD3 mAb (Foralumab) downregulates NKG7 and increases TGFB1 and GIMAP7 expression in T cells in subjects with COVID-19.
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DOI: 10.1073/pnas.2220272120
Abstract: Significance Activated T cells play an important role in the complications following COVID-19 infection. Anti-CD3 monoclonal antibody (mAb) binds to the T cell receptor and dampens inflammation by modulating T cell function. We show here… read more here.
Keywords: anti cd3; mab foralumab; cd3 mab; nasal administration ... See more keywords