MAB21L4 deficiency drives squamous cell carcinoma via activation of RET.
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DOI: 10.1158/0008-5472.can-22-0047
Abstract: Epithelial squamous cell carcinomas (SCC) most commonly originate in the skin, where they display disruptions in the normally tightly regulated homeostatic balance between keratinocyte proliferation and terminal differentiation. We performed a transcriptome-wide screen for genes… read more here.
Keywords: scc; squamous cell; ret; differentiation ... See more keywords