Discovery of an antivirulence compound that reverses β-lactam resistance in MRSA
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DOI: 10.1038/s41589-019-0401-8
Abstract: Staphylococcus aureus is the leading cause of infections worldwide, and methicillin-resistant strains (MRSA) are emerging. New strategies are urgently needed to overcome this threat. Using a cell-based screen of ~45,000 diverse synthetic compounds, we discovered… read more here.
Keywords: reverses lactam; antivirulence; virulence; lactam resistance ... See more keywords