Induced Cognitive Impairments Reversed by Grafts of Neural Precursors: A Longitudinal Study in a Macaque Model of Parkinson's Disease
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202103827
Abstract: Parkinson's disease (PD) evolves over an extended and variable period in humans; years prior to the onset of classical motor symptoms, sleep and biological rhythm disorders develop, significantly impacting the quality‐of‐life of patients. Circadian‐rhythm disorders… read more here.
Keywords: macaque model; neural precursors; disease; parkinson disease ... See more keywords
Neural Mechanism of Blindsight in a Macaque Model
Sign Up to like & getrecommendations! Published in 2021 at "Neuroscience"
DOI: 10.1016/j.neuroscience.2021.06.022
Abstract: Some patients with damage to the primary visual cortex (V1) exhibit visuomotor ability, despite loss of visual awareness, a phenomenon termed "blindsight". We review a series of studies conducted mainly in our laboratory on macaque… read more here.
Keywords: cognitive capabilities; blindsight macaque; neural mechanism; model ... See more keywords
Upregulation of Superoxide Dismutase 2 by Astrocytes in the SIV/Macaque Model of HIV-Associated Neurologic Disease.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of neuropathology and experimental neurology"
DOI: 10.1093/jnen/nlaa084
Abstract: HIV-associated neurocognitive disorders (HAND) remain prevalent despite implementation of antiretroviral therapy (ART). Development of HAND is linked to mitochondrial dysfunction and oxidative stress in the brain; therefore, upregulation of antioxidant defenses is critical to curtail… read more here.
Keywords: hiv; macaque model; siv; siv infected ... See more keywords
A Macaque Model for Rectal Lymphogranuloma Venereum and Non-Lymphogranuloma Venereum Chlamydia trachomatis: Impact on Rectal Simian/Human Immunodeficiency Virus Acquisition
Sign Up to like & getrecommendations! Published in 2017 at "Sexually Transmitted Diseases"
DOI: 10.1097/olq.0000000000000644
Abstract: Background Sustained genital tract inflammation caused by sexually transmitted infections (STIs) is known to increase risk of vaginal human immunodeficiency virus (HIV) infections but, to our knowledge, there are no nonhuman primate studies that have… read more here.
Keywords: macaque model; acquisition; lymphogranuloma venereum; immunodeficiency virus ... See more keywords
S06.3 Pigtailed macaque model of STIs
Sign Up to like & getrecommendations! Published in 2019 at "Sexually Transmitted Infections"
DOI: 10.1136/sextrans-2019-sti.38
Abstract: The Public Health Problem: Sexually transmitted infections (STIs) and their sequelae disproportionally affect young women, with cervical infections frequently ascending to the upper genital tract, leading to reproductive, pregnancy-related and newborn morbidity. Attributes of this… read more here.
Keywords: infection; tract; stis; model ... See more keywords