Genetic polymorphisms of microRNA machinery genes predict overall survival of esophageal squamous carcinoma
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.22170
Abstract: MicroRNA (miRNA)‐related single nucleotide polymorphisms (miR‐SNPs) in miRNA processing machinery genes are implicated in carcinogenesis, as they change the expression profiles of miRNA. Six miR‐SNPs in miRNA processing machinery genes, including Dicer (rs3742330), RAN (rs14035),… read more here.
Keywords: carcinoma; esophageal squamous; machinery; genetic polymorphisms ... See more keywords
Individual and joint effects of genetic polymorphisms in microRNA-machinery genes on congenital heart disease susceptibility.
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DOI: 10.1017/s1047951120004874
Abstract: Single-nucleotide polymorphisms in miRNA-machinery genes may alter the biogenesis of miRNAs affecting disease susceptibility. In this case-control study, we aimed to evaluate the impact of three single-nucleotide polymorphisms (DICER rs1057035, DROSHA rs10719, and XPO5 rs11077)… read more here.
Keywords: chd; machinery genes; disease susceptibility; risk ... See more keywords
Association between SNPs in microRNA machinery genes and gastric cancer susceptibility, invasion, and metastasis in Chinese Han population
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DOI: 10.18632/oncotarget.21199
Abstract: Objective The present study investigates the influence of genetic variants in miRNA machinery genes (DROSHA, DICER, AGO1, and GEMIN4) on gastric cancer in Chinese Han population, further revealing the genetic mechanisms of gastric cancer occurrence… read more here.
Keywords: chinese han; gastric cancer; metastasis; han population ... See more keywords
Genetic polymorphisms of miRNA machinery genes in bicuspid aortic valve and associated aortopathy.
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DOI: 10.2217/pme-2020-0082
Abstract: Aim: SNPs in miRNA machinery genes may affect miRNA function by impacting their biogenesis. Here, we investigated the association between three SNPs in miRNA machinery genes (DICER rs1057035, DROSHA rs10719 and XPO5 rs11077) and bicuspid… read more here.
Keywords: bav; mirna machinery; machinery genes; aortic valve ... See more keywords