The Translational Machinery of Human CD4+ T Cells Is Poised for Activation and Controls the Switch from Quiescence to Metabolic Remodeling.
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DOI: 10.1016/j.cmet.2018.08.009
Abstract: Naive T cells respond to T cell receptor (TCR) activation by leaving quiescence, remodeling metabolism, initiating expansion, and differentiating toward effector T cells. The molecular mechanisms coordinating the naive to effector transition are central to the functioning of… read more here.
Keywords: translational machinery; quiescence; human cd4; machinery human ... See more keywords