Pharmacological and molecular characterization of the A‐type muscarinic acetylcholine receptor from Anopheles gambiae
Sign Up to like & getrecommendations! Published in 2022 at "Insect Molecular Biology"
DOI: 10.1111/imb.12775
Abstract: Muscarinic acetylcholine receptors (mAChRs) which are G protein‐coupled receptors play key roles in insect physiology. Whereas vertebrate mAChRs are important targets for pharmaceutical drugs, insect mAChRs are under‐exploited by the agro‐chemical industry. Moreover, insect mAChRs… read more here.
Keywords: machr; anopheles gambiae; pharmacological molecular; insect machrs ... See more keywords
Cell-type-specific synaptic modulation of mAChR on SST and PV interneurons
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Psychiatry"
DOI: 10.3389/fpsyt.2022.1070478
Abstract: The muscarinic acetylcholine receptor (mAChR) antagonist, scopolamine, has been shown to have a rapid antidepressant effect. And it is believed that GABAergic interneurons play a crucial role in this action. Therefore, characterizing the modulation effects… read more here.
Keywords: machr; sst interneurons; modulation; type specific ... See more keywords