Articles with "macitentan" as a keyword



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Prospective clinical assessment of patients with pulmonary arterial hypertension switched from bosentan to macitentan (POTENT)

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Published in 2022 at "Pulmonary Circulation"

DOI: 10.1002/pul2.12083

Abstract: Abstract Even though pulmonary arterial hypertension (PAH) remains an incurable disease, the combination of PAH‐specific therapies allowed evolving from symptom‐based strategies to others aiming to move patients to low‐risk conditions. Endothelin‐1 (ET‐1) receptor antagonists emerged… read more here.

Keywords: arterial hypertension; macitentan; potent; pulmonary arterial ... See more keywords
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The Transition From Ambrisentan to Macitentan in Patients With Pulmonary Arterial Hypertension: A Real-word Prospective Study

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Published in 2022 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2021.811700

Abstract: Background: In a long-term event-driven trial, macitentan has demonstrated beneficial time to clinical worsening in patients with pulmonary arterial hypertension (PAH) and reduced PAH-related hospitalization rates compared with placebo. Macitentan is the most recently approved… read more here.

Keywords: macitentan; ambrisentan macitentan; pah patients; transition ... See more keywords