Articles with "macrocycles resin" as a keyword



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Rigid Peptide Macrocycles from On‐Resin Glaser Stapling

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Published in 2018 at "ChemBioChem"

DOI: 10.1002/cbic.201800121

Abstract: Peptide macrocycles are widely utilized in the development of high affinity ligands, including stapled α‐helices. The linear rigidity of a 1,3‐diynyl linkage provides an optimal distance (7 Å) between β‐carbons of the i,i+4 amino acid side… read more here.

Keywords: peptide; peptide macrocycles; macrocycles resin; resin glaser ... See more keywords