Histone variant macroH2A: from chromatin deposition to molecular function.
Sign Up to like & getrecommendations! Published in 2019 at "Essays in biochemistry"
DOI: 10.1042/ebc20180062
Abstract: The eukaryotic genome is regulated in the context of chromatin. Specialized histones, known as histone variants, incorporate into chromatin to replace their canonical counterparts and represent an important layer of regulation to diversify the structural… read more here.
Keywords: chromatin; chromatin deposition; histone variant; histone ... See more keywords
Functional Impact of MacroH2A Histone Variants in Acute Myeloid Leukemia
Sign Up to like & getrecommendations! Published in 2019 at "Blood"
DOI: 10.1182/blood-2019-122099
Abstract: Histone variants are emerging as key regulatory molecules in cancer. Recent data provided first evidence of how transcriptional deregulation and changes in the deposition of histone variants may affect malignant transformation. H2A variants are highly… read more here.
Keywords: functional impact; histone variants; macroh2a; h2afy ... See more keywords