Articles with "macrolide resistance" as a keyword



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Treatment of Mycobacterium abscessus Pulmonary Disease.

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Published in 2021 at "Chest"

DOI: 10.1016/j.chest.2021.07.035

Abstract: Mycobacterium abscessus is the second most common nontuberculous mycobacterial lung disease pathogen and comprises three subspecies, abscessus, massiliense and bolletii. Subspecies identification is critical for disease management as subspecies abscessus and bolletii have an inducible… read more here.

Keywords: treatment; disease; abscessus; macrolide resistance ... See more keywords

Mycoplasma genitalium macrolide resistance update: Rate among a 2016-2017 cohort of patients in Barcelona, Spain.

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Published in 2019 at "Enfermedades infecciosas y microbiologia clinica"

DOI: 10.1016/j.eimc.2019.06.008

Abstract: INTRODUCTION Mycoplasma genitalium is a major cause of urethritis and other genital syndromes. Antibiotic resistance, especially to macrolides, is increasing at an alarming rate worldwide. The aim of this study was to estimate the rate… read more here.

Keywords: 2016 2017; resistance; rate; macrolide resistance ... See more keywords

Detection of macrolide resistance genes in culture-negative specimens from Bangladeshi children with invasive pneumococcal diseases.

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Published in 2017 at "Journal of global antimicrobial resistance"

DOI: 10.1016/j.jgar.2016.11.009

Abstract: OBJECTIVES In recent years, an increasing prevalence of macrolide resistance among pneumococci in Bangladesh has been observed. However, the scenario remains incomplete, as few isolates (80%) are culture-negative. This study optimised a triplex PCR method… read more here.

Keywords: detection; resistance; macrolide resistance; culture negative ... See more keywords

Investigation of Macrolide Resistance Genotypes of Pasteurella multocida Isolates from Cattle and Small Ruminants.

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Published in 2022 at "Microbial drug resistance"

DOI: 10.1089/mdr.2022.0010

Abstract: Macrolides are commonly used to control respiratory tract infections in ruminants, but the susceptibility of Pasteurella multocida strains has shown a decrease to macrolide antibiotics in the last decade. In this work we assessed the… read more here.

Keywords: macrolide; small ruminants; pasteurella multocida; macrolide resistance ... See more keywords

Development of a Real-Time PCR Assay for Detection of Macrolide Resistance Mutations in Mycoplasma genitalium and Its Application for Epidemiological Surveillance in Russia.

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Published in 2023 at "Microbial drug resistance"

DOI: 10.1089/mdr.2022.0131

Abstract: A real-time PCR assay based on probe fluorescence quenching by a primer was developed and validated for detection of macrolide resistance (MR)-associated mutations in the 23S rRNA gene of Mycoplasma genitalium. The assay involves identification… read more here.

Keywords: detection macrolide; time pcr; macrolide resistance; resistance ... See more keywords

13 Inducible macrolide resistance rates and erm(41) mutation profile in Mycobacterium abscessus complex isolates at a national reference laboratory

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Published in 2025 at "American Journal of Clinical Pathology"

DOI: 10.1093/ajcp/aqaf121.440

Abstract: Mycobacterium abscessus complex (MABC) is the most common rapidly growing, nontuberculous mycobacterium (NTM) that causes chronic pulmonary disease and cutaneous infections. Resistance to macrolides, a cornerstone in rapidly growing mycobacterium (RGM) treatment, is a major… read more here.

Keywords: resistance; inducible macrolide; mycobacterium; abscessus ... See more keywords

Expression of acquired macrolide resistance genes in Haemophilus influenzae

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Published in 2017 at "Journal of Antimicrobial Chemotherapy"

DOI: 10.1093/jac/dkx290

Abstract: Objectives To investigate the phenotypic effect of expression of selected acquired macrolide resistance genes (AMRGs) in non-typeable Haemophilus influenzae (NTHi). Methods The AMRGs erm(A), erm(B) and erm(C) were cloned into Escherichia coli JM109 using the… read more here.

Keywords: haemophilus influenzae; expression; macrolide resistance; acquired macrolide ... See more keywords
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Macrolide Resistance, Clinical Features, and Cytokine Profiles in Taiwanese Children With Mycoplasma pneumoniae Infection

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Published in 2021 at "Open Forum Infectious Diseases"

DOI: 10.1093/ofid/ofab416

Abstract: Abstract Background The factors that predict the progression of Mycoplasma pneumoniae infection remain inconclusive. Therefore, we investigated macrolide resistance prevalence, M pneumoniae genotype, and clinical characteristics of childhood M pneumoniae respiratory tract infections in Taiwan.… read more here.

Keywords: infection; resistance; macrolide resistance; mycoplasma pneumoniae ... See more keywords

P-784. Early Prediction of Inducible Macrolide Resistance For Mycobacterium abscessus –Minimum Inhibitory Concentrations at Day 7 Versus Day 14

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Published in 2025 at "Open Forum Infectious Diseases"

DOI: 10.1093/ofid/ofae631.978

Abstract: Abstract Background Mycobacterium abscessus is notoriously difficult to treat. Current guidelines suggest a 14-day long incubation period and/or sequencing of erm41 to detect inducible macrolide resistance when treating pulmonary disease. However, the lengthy incubation is… read more here.

Keywords: macrolide; resistance; inducible macrolide; abscessus ... See more keywords

Sexually acquired reactive arthritis secondary to macrolide‐resistant Mycoplasma genitalium urethritis

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Published in 2022 at "Internal Medicine Journal"

DOI: 10.1111/imj.15684

Abstract: A 26-year-old heterosexual man described a 1-week history of dysuria and urinary frequency. He then developed progressively worsening left knee pain, swelling and restriction of movement resulting in presentation to hospital. There was no conjunctivitis… read more here.

Keywords: macrolide resistance; left knee; reactive arthritis; genitalium ... See more keywords

The Novel Macrolide Resistance Genes mef(D), msr(F), and msr(H) Are Present on Resistance Islands in Macrococcus canis, Macrococcus caseolyticus, and Staphylococcus aureus

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Published in 2020 at "Antimicrobial Agents and Chemotherapy"

DOI: 10.1128/aac.00160-20

Abstract: Chromosomal resistance islands containing the methicillin resistance gene mecD (McRImecD) have been reported in Macrococcus caseolyticus. Here, we identified novel macrolide resistance genes in Macrococcus canis on similar elements, called McRImsr. These elements were also… read more here.

Keywords: macrolide resistance; novel macrolide; resistance; gene ... See more keywords