Preparation of Proteins and Macromolecular Assemblies for Cryo-electron Microscopy.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9869-2_13
Abstract: Cryo-electron microscopy has become popular as the penultimate step on the road to structure determination for many proteins and macromolecular assemblies. The process of obtaining high-resolution images of a purified biomolecular complex in an electron… read more here.
Keywords: cryo electron; proteins macromolecular; microscopy; macromolecular assemblies ... See more keywords
RCSB Protein Data Bank 1D3D module: displaying positional features on macromolecular assemblies
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DOI: 10.1093/bioinformatics/btac317
Abstract: Abstract Motivation Mapping positional features from one-dimensional (1D) sequences onto three-dimensional (3D) structures of biological macromolecules is a powerful tool to show geometric patterns of biochemical annotations and provide a better understanding of the mechanisms… read more here.
Keywords: rcsb protein; macromolecular assemblies; data bank; positional features ... See more keywords
Building Biological Relevance Into Integrative Modelling of Macromolecular Assemblies
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2022.826136
Abstract: Recent advances in structural biophysics and integrative modelling methods now allow us to decipher the structures of large macromolecular assemblies. Understanding the dynamics and mechanisms involved in their biological function requires rigorous integration of all… read more here.
Keywords: relevance integrative; biological relevance; macromolecular assemblies; integrative modelling ... See more keywords