Dimerization of the Peptide CXCR4-Antagonist on Macromolecular and Supramolecular Protraction Arms Affords Increased Potency and Enhanced Plasma Stability.
Sign Up to like & getrecommendations! Published in 2022 at "Bioconjugate chemistry"
DOI: 10.1021/acs.bioconjchem.2c00034
Abstract: Peptides are prime drug candidates due to their high specificity of action but are disadvantaged by low proteolytic stability. Here, we focus on the development of stabilized analogues of EPI-X4, an endogenous peptide antagonist of… read more here.
Keywords: cxcr4 antagonist; antagonist macromolecular; dimerization peptide; stability ... See more keywords
Frontiers of Macromolecular and Supramolecular Science symposia
Sign Up to like & getrecommendations! Published in 2018 at "Polymer Chemistry"
DOI: 10.1039/c8py90063a
Abstract: Frontiers of Macromolecular and Supramolecular Science is the name given to a symposium series created in 2008, under the name Frontiers of Macromolecular Science, and continued under the new extended name. This symposium is based… read more here.
Keywords: science; macromolecular supramolecular; chemistry; frontiers macromolecular ... See more keywords