Progressive macrophage accumulation in lysosomal acid lipase deficiency
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Genetics and Metabolism Reports"
DOI: 10.1016/j.ymgmr.2020.100594
Abstract: Lysosomal acid lipase (LAL) deficiency (LAL-D) is a lysosomal lipid storage disorder in which the accumulation of cholesteryl esters and triglycerides predominantly in hepatocytes and cells of the macrophage-monocyte system is observed. The disturbance in… read more here.
Keywords: accumulation; macrophage accumulation; lysosomal acid; acid lipase ... See more keywords
LINC01094/SPI1/CCL7 Axis Promotes Macrophage Accumulation in Lung Adenocarcinoma and Tumor Cell Dissemination
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Immunology Research"
DOI: 10.1155/2022/6450721
Abstract: Objective Infiltration of tumor-associated macrophages is closely linked to the malignant development of human cancers. This research studies the function of C-C motif chemokine ligand 7 (CCL7) in the macrophage accumulation in lung adenocarcinoma (LUAD)… read more here.
Keywords: lung adenocarcinoma; accumulation lung; ccl7; macrophage accumulation ... See more keywords
Abstract Th0043: In vivo CRISPR-Screening Identifies Fhl3 as a Potential Regulator of Macrophage Accumulation in Atherosclerotic Plaques
Sign Up to like & getrecommendations! Published in 2025 at "Arteriosclerosis, Thrombosis, and Vascular Biology"
DOI: 10.1161/atv.45.suppl_1.th0043
Abstract: Atherosclerotic cardiovascular disease (ASCVD) is the leading cause of death and disability worldwide. Recent clinical trials have shown that inflammation plays a critical role in ASCVD. Plaque inflammation is primarily driven by inflammatory macrophage accumulation… read more here.
Keywords: macrophage function; macrophage; vivo crispr; crispr ... See more keywords
Apoptosis inhibitor of macrophage depletion decreased M1 macrophage accumulation and the incidence of cardiac rupture after myocardial infarction in mice
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0187894
Abstract: Background Cardiac rupture is an important cause of death in the acute phase after myocardial infarction (MI). Macrophages play a pivotal role in cardiac remodeling after MI. Apoptosis inhibitor of macrophage (AIM) is secreted specifically… read more here.
Keywords: aim; macrophage accumulation; cardiac rupture; macrophage ... See more keywords