Bcl6 modulates innate immunity by controlling macrophage activity and plays critical role in experimental autoimmune encephalomyelitis
Sign Up to like & getrecommendations! Published in 2020 at "European Journal of Immunology"
DOI: 10.1002/eji.201948299
Abstract: The B‐cell CLL/lymphoma 6 (Bcl6) oncogenic repressor is a master regulator of humoral immunity and B‐cell lymphomagenesis. Although much research has focused on its regulation and function of GC B cells and T cells, the… read more here.
Keywords: innate immunity; bcl6; role; macrophage activity ... See more keywords
Modulation of human macrophage activity by Ascaris antigens is dependent on macrophage polarization state.
Sign Up to like & getrecommendations! Published in 2018 at "Immunobiology"
DOI: 10.1016/j.imbio.2017.11.003
Abstract: Parasitic worms (helminths) are known to actively modulate host immune responses and inflammation. The aim of this study was to investigate if adult body fluid (ABF) from the helminth Ascaris suum has immunomodulatory effects on… read more here.
Keywords: polarization; modulation human; macrophage; macrophage activity ... See more keywords
Anti-CD47 Agent Boosts Macrophage Activity in NHL.
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DOI: 10.1158/2159-8290.cd-nb2018-155
Abstract: The anti-CD47 drug Hu5F9-G4, also known as 5F9, in combination with the anti-CD20 therapy rituximab, may be a promising treatment for some forms of non-Hodgkin lymphoma because it allows macrophages to recognize and attack cancer… read more here.
Keywords: agent boosts; macrophage activity; activity nhl; anti cd47 ... See more keywords
Comparative studies evaluating macrophage activity of pulmonary tuberculosis patients with and without diabetes mellitus (tb-dm and non tb-dm)
Sign Up to like & getrecommendations! Published in 2018 at "Bangladesh Journal of Medical Science"
DOI: 10.3329/bjms.v17i1.35290
Abstract: Background : Macrophages, as the first defense mechanism in Mycobacterium tuberculosis infection, play the important role in pulmonary TB pathogenesis. The increasing prevalence of pulmonary TB is followed by the increasing prevalence of diabetes mellitus… read more here.
Keywords: diabetes mellitus; tuberculosis; macrophage activity; activity ... See more keywords
Pseudomonas aeruginosa LasB Subverts Alveolar Macrophage Activity by Interfering With Bacterial Killing Through Downregulation of Innate Immune Defense, Reactive Oxygen Species Generation, and Complement Activation
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DOI: 10.3389/fimmu.2018.01675
Abstract: Pseudomonas aeruginosa (P.a) is a pathogen causing significant morbidity and mortality, in particular, in hospital patients undergoing ventilation and in patients with cystic fibrosis. Among the virulence factors secreted or injected into host cells, the… read more here.
Keywords: reactive oxygen; pseudomonas aeruginosa; alveolar macrophage; macrophage activity ... See more keywords
Bidirectional Regulation of Sodium Acetate on Macrophage Activity and Its Role in Lipid Metabolism of Hepatocytes
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24065536
Abstract: Short-chain fatty acids (SCFAs) are important metabolites of the intestinal flora that are closely related to the development of non-alcoholic fatty liver disease (NAFLD). Moreover, studies have shown that macrophages have an important role in… read more here.
Keywords: sodium acetate; role; macrophage activity; activity ... See more keywords
1,2-Dihydroxyxanthone: Effect on A375-C5 Melanoma Cell Growth Associated with Interference with THP-1 Human Macrophage Activity
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DOI: 10.3390/ph12020085
Abstract: Xanthones have been suggested as prospective candidates for cancer treatment. 1,2- dihydroxyxanthone (1,2-DHX) is known to interfere with the growth of several cancer cell lines. We investigated the effects of 1,2-DHX on the growth of… read more here.
Keywords: melanoma; cell; macrophage; macrophage activity ... See more keywords