Human Macrophage Long Intergenic Noncoding RNA, SIMALR, Suppresses Inflammatory Macrophage Apoptosis via NTN1 (Netrin-1)
Sign Up to like & getrecommendations! Published in 2022 at "Arteriosclerosis, Thrombosis, and Vascular Biology"
DOI: 10.1161/atvbaha.122.318353
Abstract: Background: Long noncoding RNAs (lncRNAs) have emerged as novel regulators of macrophage biology and inflammatory cardiovascular diseases. However, studies focused on lncRNAs in human macrophage subtypes, particularly human lncRNAs that are not conserved in rodents,… read more here.
Keywords: simalr; human macrophage; macrophage; biology ... See more keywords
Notch signaling is involved in regulation of LPS-induced macrophage apoptosis through JNK/NF-kB signaling pathway.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of biological regulators and homeostatic agents"
DOI: 10.23812/19-283-a
Abstract: Notch signaling plays a critical role in the development and function of macrophages. The aim of the present study was to investigate the relationship between Notch signaling pathway and macrophage apoptosis after LPS stimulation. In… read more here.
Keywords: expression; notch signaling; macrophage apoptosis; jnk ... See more keywords
Ginkgolic acid promotes inflammation and macrophage apoptosis via SUMOylation and NF-κB pathways in sepsis
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2022.1108882
Abstract: Background Excessive inflammation and increased apoptosis of macrophages contribute to organ damage and poor prognosis of sepsis. Ginkgolic acid (GA) is a natural constituent extracted from the leaves of Ginkgo biloba, that can regulate inflammation… read more here.
Keywords: apoptosis; sumoylation; inflammation macrophage; promotes inflammation ... See more keywords
Intelligent Mechanisms of Macrophage Apoptosis Subversion by Mycobacterium
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DOI: 10.3390/pathogens9030218
Abstract: Macrophages are one of the first innate defense barriers and play an indispensable role in communication between innate and adaptive immune responses, leading to restricted Mycobacterium tuberculosis (Mtb) infection. The macrophages can undergo programmed cell… read more here.
Keywords: intelligent mechanisms; mycobacterium; mechanisms macrophage; apoptosis ... See more keywords