Kaempferol impedes IL-32-induced monocyte-macrophage differentiation.
Sign Up to like & getrecommendations! Published in 2017 at "Chemico-biological interactions"
DOI: 10.1016/j.cbi.2017.07.010
Abstract: Kaempferol possesses a wide range of therapeutic properties, including antioxidant, anti-inflammatory, and anticancer properties. The present study sought to evaluate the effects and possible pharmacological mechanisms of kaempferol on interleukin (IL)-32-induced monocyte-macrophage differentiation. In this… read more here.
Keywords: kaempferol; macrophage differentiation; monocyte macrophage; macrophage ... See more keywords
Glycolytic Stimulation Is Not a Requirement for M2 Macrophage Differentiation.
Sign Up to like & getrecommendations! Published in 2018 at "Cell metabolism"
DOI: 10.1016/j.cmet.2018.08.012
Abstract: Enhanced glucose uptake and a switch to glycolysis are key traits of M1 macrophages, whereas enhanced fatty acid oxidation and oxidative phosphorylation are the main metabolic characteristics of M2 macrophages. Recent studies challenge this traditional… read more here.
Keywords: oxidative phosphorylation; differentiation; macrophage differentiation; glycolytic stimulation ... See more keywords
The Transcriptional Network That Controls Growth Arrest and Macrophage Differentiation in the Human Myeloid Leukemia Cell Line THP-1
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2020.00498
Abstract: The response of the human acute myeloid leukemia cell line THP-1 to phorbol esters has been widely studied to test candidate leukemia therapies and as a model of cell cycle arrest and monocyte-macrophage differentiation. Here… read more here.
Keywords: pma; time course; cell; macrophage differentiation ... See more keywords
Systematic Construction and Validation of a Novel Macrophage Differentiation–Associated Prognostic Model for Clear Cell Renal Cell Carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.877656
Abstract: Background: Clear cell renal cell carcinoma (ccRCC) is a malignant tumor of the human urinary system. Macrophage differentiation is associated with tumorigenesis. Therefore, exploring the prognostic value of macrophage differentiation–associated genes (MDGs) may contribute to… read more here.
Keywords: cell; ccrcc; macrophage differentiation; differentiation associated ... See more keywords
Non-heme iron overload impairs monocyte to macrophage differentiation via mitochondrial oxidative stress
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.998059
Abstract: Iron is a key element for systemic oxygen delivery and cellular energy metabolism. Thus regulation of systemic and local iron metabolism is key for maintaining energy homeostasis. Significant changes in iron levels due to malnutrition… read more here.
Keywords: iron; macrophage differentiation; iron overload;
PMA-Induced THP-1 Macrophage Differentiation is Not Impaired by Citrate-Coated Platinum Nanoparticles
Sign Up to like & getrecommendations! Published in 2017 at "Nanomaterials"
DOI: 10.3390/nano7100332
Abstract: The innate immune system consists of several complex cellular and molecular mechanisms. During inflammatory responses, blood-circulating monocytes are driven to the sites of inflammation, where they differentiate into tissue macrophages. The research of novel nanomaterials… read more here.
Keywords: platinum nanoparticles; citrate coated; macrophage differentiation; macrophage ... See more keywords
Overexpression of S100A9 in obesity impairs macrophage differentiation via TLR4-NFkB-signaling worsening inflammation and wound healing
Sign Up to like & getrecommendations! Published in 2022 at "Theranostics"
DOI: 10.7150/thno.67174
Abstract: Rationale: In obesity the fine-tuned balance of macrophage phenotypes is disturbed towards a dominance of pro-inflammatory macrophages resulting in exacerbation and persistence of inflammation and impaired tissue repair. However, the underlying mechanisms are still poorly… read more here.
Keywords: macrophage differentiation; s100a9; obesity; macrophage ... See more keywords
Gene expression during THP-1 differentiation is influenced by vitamin D3 and not vibrational mechanostimulation
Sign Up to like & getrecommendations! Published in 2021 at "PeerJ"
DOI: 10.7717/peerj.11773
Abstract: Background In injury or infection, monocytes migrate into the affected tissues from circulation and differentiate into macrophages which are subsequently involved in the inflammatory responses. Macrophage differentiation and activation have been studied in response to… read more here.
Keywords: 000 vibrations; macrophage differentiation; expression; differentiation ... See more keywords