Macrophage efferocytosis in health and disease
Sign Up to like & getrecommendations! Published in 2023 at "Cell Biochemistry and Function"
DOI: 10.1002/cbf.3780
Abstract: Creating cellular homeostasis within a defined tissue typically relates to the processes of apoptosis and efferocytosis. A great example here is cell debris that must be removed to prevent unwanted inflammatory responses and then reduce… read more here.
Keywords: efferocytosis; macrophage efferocytosis; efferocytosis health; health disease ... See more keywords
Macrophage Efferocytosis in Cardiac Pathophysiology and Repair.
Sign Up to like & getrecommendations! Published in 2020 at "Shock"
DOI: 10.1097/shk.0000000000001625
Abstract: As an integral component of cardiac tissue, macrophages are critical for cardiac development, adult heart homeostasis, as well as cardiac healing. One fundamental function of macrophages involves the clearance of dying cells or debris, a… read more here.
Keywords: efferocytosis; pathophysiology repair; cardiac pathophysiology; macrophage efferocytosis ... See more keywords
Macrophage efferocytosis in atherosclerosis
Sign Up to like & getrecommendations! Published in 2022 at "Scandinavian Journal of Immunology"
DOI: 10.1111/sji.13251
Abstract: This paper presents the role of macrophage efferocytosis, the process of elimination of apoptotic bodies—elements formed during vascular atherosclerosis. The mechanisms of macrophage efferocytosis are presented, introducing the specific signals of this process, that is,… read more here.
Keywords: efferocytosis; macrophage efferocytosis; efferocytosis atherosclerosis; vascular atherosclerosis ... See more keywords
1,25(OH)2D3 Promotes Macrophage Efferocytosis Partly by Upregulating ASAP2 Transcription via the VDR-Bound Enhancer Region and ASAP2 May Affect Antiviral Immunity
Sign Up to like & getrecommendations! Published in 2022 at "Nutrients"
DOI: 10.3390/nu14224935
Abstract: The active form of vitamin D3, i.e., 1,25(OH)2D3, exerts an anti-inflammatory effect on the immune system, especially macrophage-mediated innate immunity. In a previous study, we identified 1,25(OH)2D3-responsive and vitamin D receptor (VDR)-bound super-enhancer regions in… read more here.
Keywords: enhancer region; vdr bound; macrophage efferocytosis; asap2 ... See more keywords
SIRT6-regulated macrophage efferocytosis epigenetically controls inflammation resolution of diabetic periodontitis
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DOI: 10.7150/thno.78878
Abstract: Rationale: Diabetes exacerbates the prevalence and severity of periodontitis, leading to severe periodontal destruction and ultimately tooth loss. Delayed resolution of inflammation is a major contributor to diabetic periodontitis (DP) pathogenesis, but the underlying mechanisms… read more here.
Keywords: sirt6; inflammation; periodontitis; macrophage efferocytosis ... See more keywords
Down-regulated GAS6 impairs synovial macrophage efferocytosis and promotes obesity-associated osteoarthritis
Sign Up to like & getrecommendations! Published in 2023 at "eLife"
DOI: 10.7554/elife.83069
Abstract: Obesity has always been considered a significant risk factor in osteoarthritis (OA) progression, but the underlying mechanism of obesity-related inflammation in OA synovitis remains unclear. The present study found that synovial macrophages infiltrated and polarized… read more here.
Keywords: macrophage efferocytosis; obesity; obesity associated; macrophage ... See more keywords