Articles with "macrophage gch1" as a keyword



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Regulation of mycobacterial infection by macrophage Gch1 and tetrahydrobiopterin

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Published in 2018 at "Nature Communications"

DOI: 10.1038/s41467-018-07714-9

Abstract: Inducible nitric oxide synthase (iNOS) plays a crucial role in controlling growth of Mycobacterium tuberculosis (M.tb), presumably via nitric oxide (NO) mediated killing. Here we show that leukocyte-specific deficiency of NO production, through targeted loss… read more here.

Keywords: control; infection; gch1 tetrahydrobiopterin; mycobacterial infection ... See more keywords