All‐Natural Immunomodulatory Bioadhesive Hydrogel Promotes Angiogenesis and Diabetic Wound Healing by Regulating Macrophage Heterogeneity
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Science"
DOI: 10.1002/advs.202206771
Abstract: Macrophages are highly heterogeneous and exhibit a diversity of functions and phenotypes. They can be divided into pro‐inflammatory macrophages (M1) and anti‐inflammatory macrophages (M2). Diabetic wounds are characterized by a prolonged inflammatory phase and difficulty… read more here.
Keywords: diabetic wound; inflammatory; wound healing; macrophage heterogeneity ... See more keywords
The Contribution of Hepatic Macrophage Heterogeneity during Liver Regeneration after Partial Hepatectomy in Mice
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Immunology Research"
DOI: 10.1155/2022/3353250
Abstract: Methods In the present study, we investigated hepatic macrophage heterogeneity in murine liver regeneration after 2/3 PHx through immunofluorescence staining, fluorescence-activated cell sorting analysis, and quantitative reverse transcription-polymerase chain reaction. Results Our research showed that… read more here.
Keywords: hepatic macrophage; macrophage; liver regeneration; macrophage heterogeneity ... See more keywords
Single-cell proteomic and transcriptomic analysis of macrophage heterogeneity using SCoPE2
Sign Up to like & getrecommendations! Published in 2021 at "Genome Biology"
DOI: 10.1186/s13059-021-02267-5
Abstract: Background Macrophages are innate immune cells with diverse functional and molecular phenotypes. This diversity is largely unexplored at the level of single-cell proteomes because of the limitations of quantitative single-cell protein analysis. Results To overcome… read more here.
Keywords: single cell; analysis; cell; macrophage heterogeneity ... See more keywords
The versatility of macrophage heterogeneity in liver fibrosis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.968879
Abstract: Liver fibrosis is a highly conserved wound healing response to liver injury, characterized by excessive deposition of extracellular matrix (ECM) in the liver which might lead to loss of normal functions. In most cases, many… read more here.
Keywords: liver fibrosis; macrophage heterogeneity; versatility macrophage; heterogeneity liver ... See more keywords
Macrophage Heterogeneity in the Immunopathogenesis of Tuberculosis
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2018.01028
Abstract: Macrophages play a central role in tuberculosis, as the site of primary infection, inducers and effectors of inflammation, innate and adaptive immunity, as well as mediators of tissue destruction and repair. Early descriptions by pathologists… read more here.
Keywords: immunopathogenesis tuberculosis; heterogeneity; heterogeneity immunopathogenesis; tuberculosis ... See more keywords